Which of the following is the definition of clonal selection?

Clonal selection is a process proposed to explain how a single B or T cell that recognizes an antigen that enters the body is selected from the pre-existing cell pool of differing antigen specificities and then reproduced to generate a clonal cell population that eliminates the antigen.

What is the process of clonal selection?

When an antigen encounters the immune system, its epitopes eventually will react only with B-lymphocytes with B-cell receptors on their surface that more or less fit and this activates those B-lymphocytes. This process is known as clonal selection.

What is clonal selection quizlet?

clonal selection. –antigenic-specific selection of a lymphocyte that activates it to produce clones of effector cells dedicated to eliminating the antigen that provoked the initial immune response.

What makes agglutination by antibodies possible what makes agglutination by antibodies possible?

What makes agglutination by antibodies possible? Each antibody has at least two antigen-binding sites. … The antibodies may block proteins necessary for binding the pathogen to the host, may opsonize the bacterium, or may agglutinate bacteria.

What is an example of clonal selection?

Clonal selection theory of lymphocytes: 1) A hematopoietic stem cell undergoes differentiation and genetic rearrangement to produce 2) immature lymphocytes with many different antigen receptors. Those that bind to 3) antigens from the body’s own tissues are destroyed, while the rest mature into 4) inactive lymphocytes.

Which of the following is are characteristics of a plasma cell?

Plasma cells are large lymphocytes with abundant cytoplasm and a characteristic appearance on light microscopy. They have basophilic cytoplasm and an eccentric nucleus with heterochromatin in a characteristic cartwheel or clock face arrangement.

What occurs during agglutination?

Agglutination is the process that occurs if an antigen is mixed with its corresponding antibody called isoagglutinin. … The clumping of cells such as bacteria or red blood cells in the presence of an antibody or complement. The antibody or other molecule binds multiple particles and joins them, creating a large complex.

What is agglutination reaction?

Agglutination reactions involve particulate antigens capable of binding antibody molecules. Since antibody molecules are multivalent, suspended particulate antigens form large clumps or aggregates, easily visible without magnification, when exposed to specific antibodies.

What causes agglutination?

Agglutination is caused by the formation of antibody-antigen complexes and occurs at room temperatures. Auto-agglutination is produced as a result of a complex formed between the patient’s own RBC antigens and antibodies, mediated by cold-reacting antibodies.

What are the types of agglutination?

There are two forms of agglutination. They are the active agglutination and the passive agglutination.

Active agglutination
  • biological technique.
  • agglutination reaction.
  • antigen.
  • antiserum.
  • sorption.
  • spontaneous aggtination.
  • immune agglutination.
  • group agglutination.

What are the two stages of agglutination reaction?

These reactions take part in two stages, sensitization and agglutination. In the first stage (sensitization), the antibody binds to the red cell or sensitizes it. In the second stage, the sensitized red cells agglutinate. Although sensitization occurs first, it and agglutination ultimately overlap to some extent.

What is agglutination and how is it used to differentiate blood type?

The agglutination indicates that the blood has reacted with a certain antibody and is therefore not compatible with blood containing that kind of antibody. If the blood does not agglutinate, it indicates that the blood does not have the antigens binding the special antibody in the reagent.

What are the 5 types of agglutination?

Various methods of agglutination are used in diagnostic immunology and these incude latex agglutination, flocculation tests, direct bacterial agglutination, and hemagglutination.

What type of reaction is agglutination?

Agglutination is defined as the formation of clumps of cells or inert particles by specific antibodies to surface antigenic components (direct agglutination) or to antigenic components adsorbed or chemically coupled to red cells or inert particles (passive hemagglutination and passive agglutination, respectively).

What is agglutination serology?

Agglutination is a serological reaction in which antibodies react with antigens on the surface of particles and cause the particles to clump together, or agglutinate. This reaction generally results in a visible mass that can be seen with the unaided eye.

What is agglutination quizlet?

Agglutination is the clumping of erythrocytes (RBC) together.

What Agglutinate means?

1 : to unite or combine into a group or mass. 2 : to form words by agglutination. agglutinate. noun. ag·​glu·​ti·​nate | \ ə-ˈglü-tə-nət , -tə-ˌnāt \

What is bacterial agglutination?

Particulate antigens, such as bacteria, combine with their specific antibodies to form complexes that usually aggregate as visible clumps. This is called bacterial agglutination.

What is the common name for agglutination?

“This clumping is spoken of as agglutination and the substances produced in the animal are called agglutinins.”

What is another word for agglutination?
accretion adhesion
clumping cohesion

How does agglutination occur quizlet?

Agglutination involves aggregation of a soluble antigen with soluble antibody to produce an insoluble complex that is visible. Agglutination is a more sensitive reaction in comparison to precipitation. More soluble antigens and soluble antibody is needed to form visible precipitation.